Chronic myelogenous leukemia in nonlymphoid blastic phase
نویسندگان
چکیده
منابع مشابه
CardiacTamponade in the Myelogenous Blastic Crisis of Chronic Leukemia
A S6-year-old man with Philadelphia chromosome-positive chronic myelogenous leukemia (CML) developed hemorrhagic pericarditis with tampbnade as a terminal manifestation of the blastic risis. Cftrdiac tamponade should be kept in mind as an uncommon cause of death of CML patients. Based on a literature review, Symptornatic pericarditis in patients with CML blast crisis suggests imminent death. Th...
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The surface antigen phenotype of 30 patients with the blast phase of chronic myeloid leukemia (CML) was determined using a panel of monoclonal antibodies recognizing differentiation antigens of normal myeloid, erythroid, megakaryocyte, and lymphoid cells. Ten patients' cells expressed a phenotype corresponding to an immature myeloid cell and were felt to have "myeloid" blast crisis. None of the...
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A 29-year-old man with an 8-year history of chronic myeloid leukemia (CML) was referred to our institution for marked leukocytosis and 3% blasts (white blood cells [WBC], 338.7 3 10/L; neutrophils, 159.2 3 10/L; myelocytes, 88.1 3 10/L; basophils, 47.43 10/L) (panel A). Cytogenetic studies showed t(9;22)(q34;q11.2), and the diagnosis of CML, chronic phase, was confirmed. The treatment history i...
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Background: Chronic myelogenous leukemia (CML) is a myeloproliferative disorder due to BCR-ABL1 translocation. Patients showing transformation into blast crisis (BC) have poorer treatment response and prognosis. Methods: A retrospective study was conducted in the department of Pathology, Maulana Azad Medical College, New Delhi, India, over a time period of 5 years (2014-2019) to evaluate the ...
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The establishment and the biological properties of a new leukemic cell line (KBM-5) derived from a patient in the blastic phase of chronic myelogenous leukemia are described. The cells exhibited multiple copies of the Philadelphia chromosome, and a high level of p210Bcr-Abl kinase activity was detected with rabbit anti-Abl and anti-Bcr (exon 3) peptide antisera. Use of specific primers and poly...
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ژورنال
عنوان ژورنال: Cancer
سال: 1999
ISSN: 0008-543X,1097-0142
DOI: 10.1002/(sici)1097-0142(19991215)86:12<2632::aid-cncr7>3.0.co;2-a